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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1351561Generated: October 31, 2026

Pyrimidine, 2,4-dichloro-5-methyl- → (2-Chloro-5-methyl-pyrimidin-4-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amine

https://huagongshe.com/reaction/1351561

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrimidine, 2,4-dichloro-5-methyl-HCID 74508—
Reactant[1-(2-Phenylethylsulfonyl)piperidin-4-yl]methanamineHCID 22135729—
Product(2-Chloro-5-methyl-pyrimidin-4-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amineHCID 23577242—

Reaction Steps

EXAMPLE 91 was prepared from C-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-yl]-methylamine and 2,4-dichloro-5-methyl-pyrimidine: MS (m+1)=410.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07217716B2
Source datasetuspto-grants-2007_05
ORD IDord-06b25082f09d456e8200c65988d29cfd
Source noteuspto-grants-2007_05