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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1351566Generated: November 3, 2026

2-Chloro-4-aminopyrimidine → HCID 23577296, compound

https://huagongshe.com/reaction/1351566

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-aminopyrimidineHCID 345752—
Reactant[1-(2-Phenylethylsulfonyl)piperidin-4-yl]methanamineHCID 22135729—
ProductHCID 23577296HCID 23577296—

Reaction Steps

EXAMPLE 96 was prepared from C-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-yl]-methylamine and 2-chloro-pyrimidin-4-ylamine (prepared from 2,4-chloro-pyrimidin-4-ylamine by hydrogenation in ethanol over 5% palladium on carbon, 1 atm of hydrogen): MS (m+1)=376.5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07217716B2
Source datasetuspto-grants-2007_05
ORD IDord-599368a68f40483f84ba2898ede79acd
Source noteuspto-grants-2007_05