HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Dioxopyrrolidin-1-yl (4-methylbenzyl) carbonate → 4-[(3-Methoxy-5-methyl-pyrazin-2-ylamino)-methyl]-piperidine-1-carboxylic acid 4-methyl-benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Dioxopyrrolidin-1-yl (4-methylbenzyl) carbonate | HCID 11139951 | — |
| Reactant | 4-[(3-Methoxy-5-methyl-pyrazin-2-ylamino)-methyl]-piperidine | HCID 22135591 | — |
| Product | 4-[(3-Methoxy-5-methyl-pyrazin-2-ylamino)-methyl]-piperidine-1-carboxylic acid 4-methyl-benzyl ester | HCID 23577301 | — |
Reaction Steps
The above compound was prepared in a similar manner as described in EXAMPLE 130 from 4-[(3-methoxy-5-methyl-pyrazin-2-ylamino)-methyl]-piperidine (EXAMPLE 130, STEP 2) using N-(4-methylbenzyloxycarbonyloxy)succinimide (INTERMEDIATE 1A). M.S. (m+1): 385.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07217716B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-e76afc5dc5984479a81dd18485b30fed |
| Source note | uspto-grants-2007_05 |