2,4-Difluorostyrene → 2-[2-({4-[(E)-2-(2,4-difluorophenyl)vinyl]phenyl}sulfonyl)phenyl]-1,3,4-oxadiazole

Participants

Reaction Steps

The title compound was prepared according to the method of preparation of Intermediate 1, Step 2, using 2-{2-[(4-bromophenyl)sulfonyl]phenyl}-1,3,4-oxadiazole (Step 1) in place of 3-[(4-bromophenyl)sulfonyl]propanenitrile and 2,4-difluorostyrene in place of 4-fluorostyrene. δH (500 MHz, d6 DMSO): 9.45 (1H, s), 8.35 (1H, d, J 7.8), 7.97–7.85 (8H, m), 7.47–7.31 (3H, m), 7.17 (1H, t, J 8.6). m/z (ES+) 425 [MH+].

Provenance & Evidence