Potassium Nitrate → 6-Cyano-4-nitro-naphthalene-2-carboxylic acid methyl ester

HRID 1351709Notes

Reaction equation

HRID 1351709 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:14]=[CH:13][C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:15]#[N:16])[CH:11]=2)[CH:6]=1)=[O:4].[N+:17]([O-])([O-:19])=[O:18].[K+]>S(=O)(=O)(O)O>[CH3:1][O:2][C:3]([C:5]1[CH:14]=[C:13]([N+:17]([O-:19])=[O:18])[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:15]#[N:16])[CH:11]=2)[CH:6]=1)=[O:4]

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 12433083Methyl 6-cyanonaphthalene-2-carboxylate

Product 1

HCID 186801146-Cyano-4-nitro-naphthalene-2-carboxylic acid methyl ester

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

Nitration of 6-cyano-naphthalene-2-carboxylic acid methyl ester, prepared as described in U.S. Pat. No. 6,284,796, is carried out with KNO3 in sulfuric acid at 0° C. for 30 min. The reaction mixture is poured into ice and filtered, and the compound is washed with water and dried. The product, 6-cyano-4-nitro-naphthalene-2-carboxylic acid methyl ester is obtained and used without further purification.

Workup

  1. additionThe reaction mixture is poured into ice
  2. filtrationfiltered
  3. washthe compound is washed with water
  4. customdried

Sources & evidence

ORD record
ord-14c3ed77a3d04228ab4610792aa14900
Source dataset
uspto-grants-2007_05
Patent number
US07217794B2

Reaction notes

Loading…