反应详情

To a solution 2-Nitro-4-(3-pyrrolidinylpropoxy)phenylamine 1 in EtOH, Pd/C (0.1 eq) is added. The reaction vessel is repeatedly purged (×3) with nitrogen, and then stirred under a hydrogen atmosphere for 18 h. The product is filtered through a Celite plug, and the plug washed with 25 mL of EtOH, to yield 2. LCMS 236.2 Rt 0.94 min.

1. customThe reaction vessel is repeatedly purged (×3) with nitrogen
2. filtrationThe product is filtered through a Celite plug
3. washthe plug washed with 25 mL of EtOH
4. customto yield 2