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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1352260Generated: November 1, 2026

1,1,1-Trifluorobutan-2-ol → 5-Methanesulfonyl-2-(1-trifluoromethyl-propoxy)-benzoic acid

https://huagongshe.com/reaction/1352260

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1,1-Trifluorobutan-2-olHCID 11332471—
Reactant2-Fluoro-5-methanesulfonyl-benzoic acidHCID 22467566—
Product5-Methanesulfonyl-2-(1-trifluoromethyl-propoxy)-benzoic acidHCID 21100302—

Reaction Steps

Prepared in analogy to Example A14(c) from 2-fluoro-5-methanesulfonyl-benzoic acid (Example A14(b)) and rac-1,1,1-trifluoro-butan-2-ol. MS (m/e): 325.0 ([M−H]−, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220744B2
Source datasetuspto-grants-2007_05
ORD IDord-4abf3ab203584d049a474df13cb36889
Source noteuspto-grants-2007_05