(-)-2-Butanol → 2-[(1R)-1-Methylpropoxy]-5-(methylsulfonyl)benzoic acid

HRID 1352261Notes

Reaction equation

HRID 1352261 reaction equation
F[C:2]1[CH:10]=[CH:9][C:8]([S:11]([CH3:14])(=[O:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[CH3:15][C@@H:16]([OH:19])[CH2:17][CH3:18]>>[C@H:16]([O:19][C:2]1[CH:10]=[CH:9][C:8]([S:11]([CH3:14])(=[O:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5])([CH2:17][CH3:18])[CH3:15]

Participants

3

Reactant 2

HCID 84682(-)-2-ButanolHCID 224675662-Fluoro-5-methanesulfonyl-benzoic acid

Product 1

HCID 588633572-[(1R)-1-Methylpropoxy]-5-(methylsulfonyl)benzoic acid

Procedure

Prepared in analogy to Example A14(c) from 2-fluoro-5-methanesulfonyl-benzoic acid (Example A14(b)) and (R)-butan-2-ol. MS (m/e): 271.1 ([M−H]−, 100%)

Sources & evidence

ORD record
ord-04bbe2d777e9416d94bd066dd488c4b3
Source dataset
uspto-grants-2007_05
Patent number
US07220744B2

Reaction notes

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