HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → 5-Methyl-2-(piperazin-1-yl)thiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | 2-Iodo-5-methyl-1,3-thiazole | HCID 23154586 | — |
| Product | 5-Methyl-2-(piperazin-1-yl)thiazole | HCID 21100190 | 32% |
Reaction Steps
Prepared in analogy to example 2 (b) from 2-iodo-5-methyl-thiazole and piperazine. The crude material was purified by chromatography (SiO2, methanol/dichloromethane) to yield the title compound as a yellow oil (yield 32%). MS (m/e): 184.3 (M+H+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220744B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-b611228972734f4c8a8d171ece5f94ad |
| Source note | uspto-grants-2007_05 |