HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 4407465, compound → HCID 21100246, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 4407465 | HCID 4407465 | — |
| Reactant | 2-Isopropoxy-5-methylsulfonylbenzoic acid | HCID 21100237 | — |
| Product | HCID 21100246 | HCID 21100246 | 67% |
Reaction Steps
Prepared in analogy to example 1 (b) from 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example A1) and 1-(5-nitro-thiazol-2-yl)-piperazine. The crude material was purified by chromatography (SiO2, ethyl acetate/heptane) followed by trituration in ether to yield the title compound as a yellow crystalline solid (yield 67%). MS (m/e): 455.4 (M+H+, 100%), 472.0 (M+NH4+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220744B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-5c8822b93e7f40b6aed2bb5155d10fe1 |
| Source note | uspto-grants-2007_05 |