huagongshe.com
HRID1352299

反应详情

EQUATION

反应方程式

HRID 1352299 的结构方程式

REACTANTS

反应物

2
结构：N#Cc1cnc(N2CCNCC2)s1
HCID21100257

未命名化合物

结构：CCC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O
HCID21100258

未命名化合物

PRODUCTS

生成物

1
结构：CCC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2ncc(C#N)s2)CC1
HCID21100214

未命名化合物

收率 34%

PROCEDURE

实验过程

Prepared in analogy to example 1 (b) from 2-sec-butoxy-5-methanesulfonyl-benzoic acid (Example A10) and 2-piperazin-1-yl-thiazole-5-carbonitrile (Example 6(a)). The crude material was purified by chromatography (SiO2, ethyl acetate/heptane) followed by trituration in ether to yield the tide compound as a white crystalline solid (yield 34%). MS (m/e): 449.4 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (SiO2, ethyl acetate/heptane)