huagongshe.com
HRID1352307

反应详情

EQUATION

反应方程式

HRID 1352307 的结构方程式

REACTANTS

反应物

2
结构：CS(=O)(=O)c1cnc(N2CCNCC2)s1.Cl
HCID21100187

未命名化合物

结构：CC(C)COc1ccc(S(C)(=O)=O)cc1C(=O)O
HCID23503110

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)COc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2ncc(S(C)(=O)=O)s2)CC1
HCID21100234

未命名化合物

收率 40%

PROCEDURE

实验过程

Prepared in analogy to example 1 (b) from 2-isobutoxy-5-methanesulfonyl-benzoic acid (Example A8) and 1-(5-methanesulfonyl-thiazol-2-yl)-piperazine hydrochloride (Example 21(c)). The crude material was purified by chromatography (SiO2, ethyl acetate/heptane) followed by trituration in ether to yield the title compound as a white crystalline solid (yield 40%). MS (m/e): 502.0 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (SiO2, ethyl acetate/heptane)