HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-(5-Ethanesulfonyl-thiazol-2-yl)-piperazine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-(5-Ethanesulfonyl-thiazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester | HCID 68406905 | — |
| Product | 1-(5-Ethanesulfonyl-thiazol-2-yl)-piperazine hydrochloride | HCID 21100185 | 86% |
Reaction Steps
Prepared in analogy to example 4 (d) from 4-(5-ethanesulfonyl-thiazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester and hydrogen chloride solution. The crude material was purified by recrystallisation from ether to afford the title compound as a light brown crystalline solid (yield 86%). MS (m/e): 262.0 (M+H+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220744B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-f48a0fb9bc5142dcadb1bd1802c56f94 |
| Source note | uspto-grants-2007_05 |