HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → 1-(4,5-Dimethyl-1,3-thiazol-2-yl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | 29947-25-9 | HCID 21100233 | — |
| Product | 1-(4,5-Dimethyl-1,3-thiazol-2-yl)piperazine | HCID 19915765 | 25% |
Reaction Steps
Prepared in analogy to example 2 (b) from 2-iodo-4,5-dimethyl-thiazole and piperazine. The crude material was purified by chromatography (SiO2, methanol/dichloromethane) to yield the title compound as a yellow crystalline solid (yield 25%). MS (m/e): 198.3 (M+H+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220744B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-44e2950f1c8f4699b6fe396b17f9de1e |
| Source note | uspto-grants-2007_05 |