反应详情

Prepared in analogy to example 1 (b) from 5-methanesulfonyl-2-methylsulfanyl-benzoic acid (Example A26) and 1-(5-trifluoromethyl-thiazol-2-yl)-piperazine hydrochloride (Example 58(c)). The crude material was purified by chromatography (SiO2, ethyl acetate/heptane) to yield the title compound as a light brown solid (yield 18%). MS (m/e): 466.0 (M+H+, 100%).

1. customThe crude material was purified by chromatography (SiO2, ethyl acetate/heptane)