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HRID1352404

反应详情

EQUATION

反应方程式

HRID 1352404 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1cc([N+](=O)[O-])ccc1N1CCOCC1
HCID2725755

2-Morpholino-5-nitrobenzoic acid

C11H12N2O5

结构：FC(F)(F)c1nnc(N2CCNCC2)s1.O=C(O)C(F)(F)F
HCID21100199

未命名化合物

PRODUCTS

生成物

1
结构：O=C(c1cc([N+](=O)[O-])ccc1N1CCOCC1)N1CCN(c2nnc(C(F)(F)F)s2)CC1
HCID21100256

未命名化合物

收率 34%

PROCEDURE

实验过程

Prepared in analogy to example 1 (b) from 2-morpholin-4-yl-5-nitro-benzoic acid (Example A27) and 1-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-piperazine trifluoroacetate (Example 62(b)). The crude material was purified by chromatography (SiO2, methanol/dichloromethane) to yield the title compound as a brown solid (yield 34%). MS (m/e): 473.4 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (SiO2, methanol/dichloromethane)