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HRID1352405

反应详情

EQUATION

反应方程式

HRID 1352405 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(F)c1nnc(N2CCNCC2)s1.O=C(O)C(F)(F)F
HCID21100199

未命名化合物

结构：CC(C)Sc1ccc(S(C)(=O)=O)cc1C(=O)O
HCID21100252

2-[(1-Methylethyl)thio]-5-(methylsulfonyl)benzoic acid

C11H14O4S2

PRODUCTS

生成物

1
结构：CC(C)Sc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2nnc(C(F)(F)F)s2)CC1
HCID21100254

未命名化合物

收率 34%

PROCEDURE

实验过程

Prepared in analogy to example 1 (b) from 2-isopropylsulfanyl-5-methanesulfonyl-benzoic acid (Example A22) and 1-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-piperazine trifluoroacetate (Example 62(b)). The crude material was purified by chromatography (SiO2, ethyl acetate/heptane) to yield the title compound as a white solid (yield 34%). MS (m/e): 495.0 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (SiO2, ethyl acetate/heptane)