huagongshe.com
HRID1352415

反应详情

EQUATION

反应方程式

HRID 1352415 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(F)c1nnc(N2CCNCC2)s1.O=C(O)C(F)(F)F
HCID21100199

未命名化合物

结构：CS(=O)(=O)c1ccc(OCC(F)(F)C(F)(F)F)c(C(=O)O)c1
HCID21100315

未命名化合物

PRODUCTS

生成物

1
结构：CS(=O)(=O)c1ccc(OCC(F)(F)C(F)(F)F)c(C(=O)N2CCN(c3nnc(C(F)(F)F)s3)CC2)c1
HCID21100316

未命名化合物

收率 56%

PROCEDURE

实验过程

Prepared in analogy to example 1 (b) from 5-methanesulfonyl-2-(2,2,3,3,3-pentafluoro-propoxy)-benzoic acid (Example A30) and 1-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-piperazine trifluoroacetate (Example 62(b)). The crude material was purified by chromatography (SiO2, methanol/dichloromethane) to yield the title compound as an off-white solid (yield 56%). MS (m/e): 569.3 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (SiO2, methanol/dichloromethane)