反应详情

Prepared in analogy to example 1 (b) from 5-methanesulfonyl-2-(2,2,3,3,3-pentafluoro-propoxy)-benzoic acid (Example A30) and 1-(5-trifluoromethyl-thiazol-2-yl)-piperazine hydrochloride (Example 58(c)). The crude material was purified by chromatography (SiO2, ethyl acetate/heptane) to yield the title compound as a brown solid (yield 68%). MS (m/e): 568.2 (M+H+, 100%).

1. customThe crude material was purified by chromatography (SiO2, ethyl acetate/heptane)