HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromobutanol → 3-[1-(4-hydroxybutyl)piperidin-4-yl]-2H-isoquinolin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromobutanol | HCID 118388 | — |
| Reactant | 3-(Piperidin-4-yl)isoquinolin-1(2H)-one hydrochloride | HCID 23082113 | — |
| Product | 3-[1-(4-hydroxybutyl)piperidin-4-yl]-2H-isoquinolin-1-one | HCID 10334983 | 8.8% |
Reaction Steps
By the reaction in the same manner as in Example 21a, using 3-(piperidin-4-yl)-2H-isoquinolin-1-one hydrochloride (500 mg) and 4-bromo-1-butanol (434 mg), 3-[1-(4-hydroxybutyl)piperidin-4-yl]-2H-isoquinolin-1-one (50 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220759B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-2c13b38340764449ad005bf05d04f7e9 |
| Source note | uspto-grants-2007_05 |