HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N,2,3-tetramethylbenzamide → 3-[2-hydroxy-3-(pyrrolidin-1-yl)propyl]-5-methyl-2H-isoquinolin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N,2,3-tetramethylbenzamide | HCID 22931034 | — |
| Reactant | 3-Hydroxy-4-(pyrrolidin-1-yl)butyronitrile | HCID 23082088 | — |
| Product | 3-[2-hydroxy-3-(pyrrolidin-1-yl)propyl]-5-methyl-2H-isoquinolin-1-one | HCID 10446711 | 1.5% |
Reaction Steps
By the reaction in the same manner as in Example 1a, using N,N-dimethyl-2,3-dimethylbenzamide (2.65 g) and 3-hydroxy-4-(pyrrolidin-1-yl)butyronitrile (2.31 g), 3-[2-hydroxy-3-(pyrrolidin-1-yl)propyl]-5-methyl-2H-isoquinolin-1-one (0.066 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220759B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-31d97024d9574ff2be1515beb76a3873 |
| Source note | uspto-grants-2007_05 |