Boron tribromide → HCID 69427096, compound

HRID 1352496Notes

Reaction equation

HRID 1352496 reaction equation
[C:1]([N:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[C@H:12]([N:19]([C:23]2[CH:28]=[CH:27][C:26]([O:29]C)=[CH:25][CH:24]=2)[C:20](=[O:22])[CH3:21])[CH2:11][C@@H:10]1[CH3:31])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.B(Br)(Br)Br>ClCCl>[C:1]([N:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[C@H:12]([N:19]([C:23]2[CH:28]=[CH:27][C:26]([OH:29])=[CH:25][CH:24]=2)[C:20](=[O:22])[CH3:21])[CH2:11][C@@H:10]1[CH3:31])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 69433494HCID 69433494, compound

Product 1

HCID 69427096HCID 69427096, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Conditions

Temperature
-78 °C

Procedure

To a solution of Cis-N-(1-Benzoyl-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-(4-methoxy-phenyl)-acetamide (0.1 g) in dichloromethane (5 ml), boron tribromide (0.18 g) was added under stirring and under cooling at −78° C. in an acetone-dry ice bath.

Sources & evidence

ORD record
ord-24a8ac68083a47fc99a3db6548629d91
Source dataset
uspto-grants-2007_05
Patent number
US07220760B2

Reaction notes

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