Bromide ion → HCID 17971729, compound

HRID 1352500Notes

Reaction equation

HRID 1352500 reaction equation
[C:1]1([N:7]([C:11]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[N:14]=[CH:13][CH:12]=2)[C:8](=[O:10])[CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br-:21]>CC(C)=O>[Br-:21].[C:8]([N:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)[C:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[N+:14]([CH2:11][C:20]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)=[CH:13][CH:12]=1)(=[O:10])[CH3:9]

Participants

4

Reactant 2

HCID 259Bromide ionHCID 22935737HCID 22935737, compound

Product 1

HCID 17971729HCID 17971729, compoundYield 121.1%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of N-phenyl-N-quinolin-4-yl-acetamide (2 g) and benzyle bromide (1.3 g) in acetone was warmed to reflux for 5 days. The solvent was removed to afford an amorphous material, which was crystallized in diethyl ether. 4-[Acetyl-(phenyl)-amino]-1-benzylquinolinium bromide (2 g) was obtained by filtration.

Workup

  1. temperatureto reflux for 5 days
  2. customThe solvent was removed
  3. customto afford an amorphous material, which
  4. customwas crystallized in diethyl ether

Sources & evidence

ORD record
ord-32ebb674b78f4cc1b4786b81ac5d05f6
Source dataset
uspto-grants-2007_05
Patent number
US07220760B2

Reaction notes

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