HuagongsheHuagongshe Chemistry Print Report · For research reference only
Camphor-10-sulfonyl chloride → n-{2-[2-(4-Amino-2,6,7-trimethyl-imidazo[4,5-c]pyridin-1-yl)-ethoxy]-ethyl}-c-(7,7-dimethyl-2-oxo-bicyclo[2.2.1]hept-1-yl)methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Camphor-10-sulfonyl chloride | HCID 88856 | — |
| Reactant | 1-[2-(2-aminoethoxy)ethyl]-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine | HCID 21913053 | — |
| Product | n-{2-[2-(4-Amino-2,6,7-trimethyl-imidazo[4,5-c]pyridin-1-yl)-ethoxy]-ethyl}-c-(7,7-dimethyl-2-oxo-bicyclo[2.2.1]hept-1-yl)methanesulfonamide | HCID 21913450 | — |
Reaction Steps
Using the method of Examples 34–50, D-(+)-10-camphorsulfonyl chloride was reacted with 1-[2-(2-aminoethoxy)ethyl]-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The product was purified using Method A. The observed accurate mass was 478.2455.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220758B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-1951e553fc86429cafacb9862ea820fd |
| Source note | uspto-grants-2007_05 |