Carbamic chloride, N-methyl-N-phenyl- → HCID 10250157, compound

HRID 1352583Notes

Reaction equation

HRID 1352583 reaction equation
[CH3:1][N:2]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[C:3](Cl)=[O:4].[NH2:12][CH2:13][CH2:14][O:15][CH2:16][CH2:17][N:18]1[C:26]2[C:25]([CH3:27])=[C:24]([CH3:28])[N:23]=[C:22]([NH2:29])[C:21]=2[N:20]=[C:19]1[CH3:30]>>[NH2:29][C:22]1[C:21]2[N:20]=[C:19]([CH3:30])[N:18]([CH2:17][CH2:16][O:15][CH2:14][CH2:13][NH:12][C:3](=[O:4])[N:2]([CH3:1])[C:6]3[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=3)[C:26]=2[C:25]([CH3:27])=[C:24]([CH3:28])[N:23]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 219130531-[2-(2-aminoethoxy)ethyl]-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine

Product 1

HCID 10250157HCID 10250157, compound

Procedure

Using the method of Examples 54–68, N-methyl-N-phenylcarbamoyl chloride was reacted with 1-[2-(2-aminoethoxy)ethyl]-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The product was purified using Method A. The observed accurate mass was 397.2343.

Sources & evidence

ORD record
ord-39d3063cb8174782bfd4620d020d63d2
Source dataset
uspto-grants-2007_05
Patent number
US07220758B2

Reaction notes

Loading…