化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 4-Cyano-2-ethoxybenzoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 4-Cyano-2-ethoxybenzoic acid | HCID 22675038 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 4-Cyano-2-ethoxybenzoyl chloride | HCID 21100743 | 99% |
反応手順
2-Ethoxy-4-cyanobenzoic acid (10 g, 52.3 mmol), prepared as in Preparation 10, and thionyl chloride (50 ml,) were refluxed in CH2Cl2 (80 ml) for 5 h. Solvent was removed under vacuum to leave 10.9 g of an off white solid (52 mmol, yield 99%) that was used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07220769B2 |
| 出典データセット | uspto-grants-2007_05 |
| ORD ID | ord-157a517639664487bcb1527f2d671db2 |
| 出典メモ | uspto-grants-2007_05 |