反应详情

A reaction tube was charged with suspension of 1 (330 mg, 1.15 mmol) and Lindlar catalyst (245 mg, 10 mol %) in methanol (5 mL), sealed, and placed on a Parr shaker. The reaction was pressurized with H2 (60 psi) and maintained for 1 h. The reaction was filtered through Celite and the remaining solids were washed with MeOH. The combined organics were concentrated to give 2 as a brown semi-solid which was taken on without further purification.

1. customsealed
2. temperaturemaintained for 1 h
3. filtrationThe reaction was filtered through Celite
4. washthe remaining solids were washed with MeOH
5. concentrationThe combined organics were concentrated