HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyanobenzoic acid → HCID 22716894, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyanobenzoic acid | HCID 15875 | — |
| Reactant | (R)-beta-aminophenethyl alcohol | HCID 2724025 | — |
| Reactant | Bis-(1H-imidazol-2-YL)-methanone | HCID 5250894 | — |
| Product | HCID 22716894 | HCID 22716894 | — |
Reaction Steps
By solution phase srategy: Typically 3-cyanobenzoic acid is activated with carbonyl-diimidazole and reacted with R-phenylglycinol to give 3-cyanobenzoylphenylglycinol. Reaction with a trichloroacetimidate and BF3 etherate, (4), gives an ether. Reaction of the cyano group with HCl in ethanol followed by ammonia in ethanol gives the amidino compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220781B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-b1f4ae3ef5cf4c6c86426d260a8df36c |
| Source note | uspto-grants-2007_05 |