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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 135301Generated: October 30, 2026

Methane → 1-[[5-[(2,5-Difluorophenyl)[(4-fluorophenyl)sulfonyl]methyl]-4-methylpyridin-2-yl]carbonyl]azetidin-3-ol

https://huagongshe.com/reaction/135301

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethaneHCID 297—
ReactantHydrochloric AcidHCID 313—
ReactantEthanolHCID 702—
Reactant4-MethylmorpholineHCID 7972—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
ReactantPalladiumHCID 23938—
Reactant1-(Diphenylmethyl)azetidin-3-olHCID 330448—
Reactant5-[(2,5-Difluorophenyl)[(4-fluorophenyl)sulfonyl]methyl]-4-methylpyridine-2-carboxylic acidHCID 57736439—
ReactantHCID 178418361HCID 178418361—
Product1-[[5-[(2,5-Difluorophenyl)[(4-fluorophenyl)sulfonyl]methyl]-4-methylpyridin-2-yl]carbonyl]azetidin-3-olHCID 57736487—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-557144f59b8643918ba356e37f9c2ed6
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)