Hydrochloric Acid → HCID 17989410, compound

Participants

Reaction Steps

4-allyloxy-2-nitro-benzoic acid allyl ester [J. Org. Chem. 1987, 52(18), 4086] (0.21 g, 0.8 mmol) was dissolved in ethanol (5 ml), and 40% sodium hydroxide added (5 ml). The mixture was stirred for 16 h then acidified to pH 2 with 2M hydrochloric acid. The mixture was extracted with ethyl acetate (3×25 ml) and the combined organic phases washed with brine (75 ml), dried (MgSO4) and concentrated to yield 4-allyloxy-2-nitrobenzoic acid as brown solid (0.16 g);

Provenance & Evidence