4-Phenoxy-2-benzofuran-1,3-dione → HCID 17989376, compound

HRID 1353093Notes

Reaction equation

HRID 1353093 reaction equation
[CH3:1][N:2]([CH2:4][CH:5]1[CH2:14][C:13]2[C:8](=[CH:9][C:10]([NH2:15])=[CH:11][CH:12]=2)[O:7][CH2:6]1)[CH3:3].[O:16]([C:23]1[CH:33]=[CH:32][CH:31]=[C:25]2[C:26](OC(=O)[C:24]=12)=O)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.[CH:34](N(C(C)C)CCOC1C=CC(N)=CC=1OC)(C)C>>[CH3:3][N:2]([CH3:1])[CH2:4][CH:5]1[CH2:14][C:13]2[C:8](=[CH:9][C:10]([N:15]3[CH2:26][C:25]4[C:31](=[CH:32][CH:33]=[C:23]([O:16][C:17]5[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=5)[CH:24]=4)[CH2:34]3)=[CH:11][CH:12]=2)[O:7][CH2:6]1

Participants

4

Reactant 3

HCID 123803714-Phenoxy-2-benzofuran-1,3-dioneHCID 186726014-{2-[Di(propan-2-yl)amino]ethoxy}-3-methoxyanilineHCID 21939924HCID 21939924, compound

Product 1

HCID 17989376HCID 17989376, compound

Procedure

3-Dimethylaminomethyl-chroman-7-ylamine[WO 0121577 A2] was treated with 3-phenoxyphthalic anhydride in the same manner as for 4-(2-diisopropylamino-ethoxy)-3-methoxy-phenylamine in Example A4 to give the title compound.

Sources & evidence

ORD record
ord-cc46421ee9a3440594c5d9d6cf7ed4ed
Source dataset
uspto-grants-2007_05
Patent number
US07220777B2

Reaction notes

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