HCID 58670155, compound → HCID 21101990, compound

Participants

Reaction Steps

To a stirred, argon-purged solution of compound 1B, (7.20 g, 28.1 mmol) in 150 mL of methanol at room temperature was added 10% Pd-on-carbon (1.0 g). The reaction mixture was purged, evacuated twice with argon and stirred under a hydrogen balloon near atmospheric pressure for 4 h. The slurry was purged with argon, filtered through a 0.45μ nylon filter and the filtrate evaporated to give the title compound (6.07 gm, 94%) as a gray solid, 95:5 diastereomeric mixture by HPLC. MS [M+Na]+: found 253.

Provenance & Evidence