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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353208Generated: October 25, 2026

3-(3-Hydroxy-phenyl)-2-methoxy-propionic acid methyl ester → 3-(3-Tert-butoxycarbonylmethoxy-phenyl)-2-methoxy-propionic acid methyl ester

https://huagongshe.com/reaction/1353208

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Hydroxy-phenyl)-2-methoxy-propionic acid methyl esterHCID 58822802—
Reactant(2S)-3-(4-tert-butoxycarbonylmethoxy-phenyl)-2-methoxy-propionic acid ethyl esterHCID 58864672—
Product3-(3-Tert-butoxycarbonylmethoxy-phenyl)-2-methoxy-propionic acid methyl esterHCID 58646648—

Reaction Steps

The title compound was prepared from 3-(3-hydroxy-phenyl)-2-methoxy-propionic acid methyl ester (example 9, step 4) via the same procedure used to prepare (2S)-3-(4-tert-butoxycarbonylmethoxy-phenyl)-2-methoxy-propionic acid ethyl ester (PREPARATION 3, step 1) to produce a yellow oil. MS (ES) for C17H24O6 [M+H]+: 325.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220880B2
Source datasetuspto-grants-2007_05
ORD IDord-4ae4982cfb494d7280c383a5943f07e3
Source noteuspto-grants-2007_05