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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353209Generated: October 25, 2026

3-(3-Tert-butoxycarbonylmethoxy-phenyl)-2-methoxy-propionic acid methyl ester → 3-(3-Carboxymethoxy-phenyl)-2-methoxy-propionic acid methyl ester

https://huagongshe.com/reaction/1353209

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Tert-butoxycarbonylmethoxy-phenyl)-2-methoxy-propionic acid methyl esterHCID 58646648—
Reactant(2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl esterHCID 58864673—
Product3-(3-Carboxymethoxy-phenyl)-2-methoxy-propionic acid methyl esterHCID 58646610—

Reaction Steps

The title compound was prepared from 3-(3-tert-butoxycarbonylmethoxy-phenyl)-2-methoxy-propionic acid methyl ester (PREPARATION 4, step 1) via the same procedure used to prepare (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester (PREPARATION 3, step 2) to produce a yellow oil. MS (ES) for C13H16O6 [M+H]+: 269.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220880B2
Source datasetuspto-grants-2007_05
ORD IDord-9fbd4c1307304f0a9d7e06a3c846138f
Source noteuspto-grants-2007_05