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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353219Generated: November 1, 2026

4-(4-Chlorobenzoyl)Piperidine → HCID 58646602, compound

https://huagongshe.com/reaction/1353219

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Chlorobenzoyl)PiperidineHCID 2777115—
Reactant(2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acidHCID 9847886—
Reactant(2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl esterHCID 58864673—
ProductHCID 58646602HCID 58646602—

Reaction Steps

The title compound was prepared from (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester (PREPARATION 3, step 2) and (4-chloro-phenyl)-piperidin-4-yl-methanone via the same procedure used for the preparation of (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a yellow oil. MS (ES) for C24H26ClNO6 [M+H]+: 460.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220880B2
Source datasetuspto-grants-2007_05
ORD IDord-92e38e264161478b8a8b485694dcc205
Source noteuspto-grants-2007_05