HRID1353230

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8764

Benzenamine, 4-phenoxy-

C12H11NO

结构：CCO[C@@H](Cc1ccc(O[C@H](C)C(=O)NCCc2ccc(Oc3ccccc3)cc2)cc1)C(=O)O

HCID9847886

未命名化合物

结构：CCOC(=O)[C@H](Cc1ccc(OC(C)(C)C(=O)O)cc1)OC

HCID58646603

未命名化合物

PRODUCTS

生成物

结构：CO[C@@H](Cc1ccc(OC(C)(C)C(=O)NCCc2ccc(Oc3ccccc3)cc2)cc1)C(=O)O

HCID10367745

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from (2S)-3-[4-(1-carboxy-1-methyl-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester (PREPARATION 5, step 2) and 4-phenoxy-phenylamine via the same procedure used for the preparation of (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a colorless oil. MS (ES) for C28H31NO6 [M+H]+: 478.

WORKUP

后处理

customto produce a colorless oil

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d3301daa5a4049cd86e4632dfb2161d0
来源数据集: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07220880B2
来源说明: uspto-grants-2007_05

反应 SMILES

C([O:3][C:4](=[O:22])[C@@H:5]([O:20][CH3:21])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][C:14]([C:17]([OH:19])=O)([CH3:16])[CH3:15])=[CH:9][CH:8]=1)C.O(C1C=CC(N)=CC=1)C1C=CC=CC=1.C(O[C@@H](CC1C=CC(O[C@@H](C(=O)[NH:55][CH2:56][CH2:57][C:58]2[CH:63]=[CH:62][C:61]([O:64][C:65]3[CH:70]=[CH:69][CH:68]=[CH:67][CH:66]=3)=[CH:60][CH:59]=2)C)=CC=1)C(O)=O)C>>[CH3:21][O:20][C@@H:5]([CH2:6][C:7]1[CH:8]=[CH:9][C:10]([O:13][C:14]([CH3:15])([C:17](=[O:19])[NH:55][CH2:56][CH2:57][C:58]2[CH:63]=[CH:62][C:61]([O:64][C:65]3[CH:70]=[CH:69][CH:68]=[CH:67][CH:66]=3)=[CH:60][CH:59]=2)[CH3:16])=[CH:11][CH:12]=1)[C:4]([OH:3])=[O:22]