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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353237Generated: October 30, 2026

2-(2-Fluorophenyl)ethylamine → HCID 10046750, compound

https://huagongshe.com/reaction/1353237

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Fluorophenyl)ethylamineHCID 643357—
Reactant(2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acidHCID 9847886—
Reactant(2S)-3-[4-(1-carboxy-1-methyl-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl esterHCID 58646603—
ProductHCID 10046750HCID 10046750—

Reaction Steps

The title compound was prepared from (2S)-3-[4-(1-carboxy-1-methyl-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester (PREPARATION 5, step 2) and 2-(2-fluoro-phenyl)-ethylamine via the same procedure used for the preparation of (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a colorless oil. MS (ES) for C22H26FNO5 [M−H]−: 402.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220880B2
Source datasetuspto-grants-2007_05
ORD IDord-bb06ce3ff0e44e51a03ac1a96ac5900f
Source noteuspto-grants-2007_05