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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353254Generated: November 1, 2026

2,6-Dichlorophenethylamine → HCID 10366679, compound

https://huagongshe.com/reaction/1353254

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-DichlorophenethylamineHCID 2734101—
Reactant(2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acidHCID 9847886—
ReactantHCID 58646552HCID 58646552—
ProductHCID 10366679HCID 10366679—

Reaction Steps

The title compound was prepared from (2S)-3-[3-(1-carboxy-1-methyl-ethoxy)-phenyl]-2-methoxy-propionic acid methyl ester (EXAMPLE 56, step 2) and 2-(2,6-dichloro-phenyl)-ethylamine via the same procedure used for the preparation of (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a colorless oil. MS (ES) for C22H25ClNO5 [M]+: 454, [M+2]+: 456.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220880B2
Source datasetuspto-grants-2007_05
ORD IDord-b4873ab161354706b92a2d3fb27068c9
Source noteuspto-grants-2007_05