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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353257Generated: November 2, 2026

2,4-Dichlorophenethylamine → HCID 10479732, compound

https://huagongshe.com/reaction/1353257

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichlorophenethylamineHCID 142938—
Reactant(2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acidHCID 9847886—
Reactant(2S)-3-[4-(1-carboxy-1-methyl-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl esterHCID 58646603—
ProductHCID 10479732HCID 10479732—

Reaction Steps

The title compound was prepared from (2S)-3-[4-(1-carboxy-1-methyl-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester (PREPARATION 5, step 2) and 2-(2,4-dichloro-phenyl)-ethylamine via the same procedure used for the preparation of (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a colorless oil. MS (ES) for C22H25Cl2NO5 [M−H]−: 452, [M+H]−: 454.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220880B2
Source datasetuspto-grants-2007_05
ORD IDord-ac78069e326b4c9d8a4b3f6c385b1d2d
Source noteuspto-grants-2007_05