2-Methyl-2-phenoxy-3-(4-{[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-methoxy}-phenyl)-propionic acid → 2-Phenoxy-2-(4-{[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-methoxy}-benzyl)-butyric acid

HRID 1353266Notes

Reaction equation

HRID 1353266 reaction equation
[CH3:1][C:2]([O:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][C:15](=[O:32])[NH:16][CH2:17][CH2:18][C:19]2[CH:24]=[CH:23][C:22]([O:25][C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)=[CH:21][CH:20]=2)=[CH:9][CH:8]=1)[C:3]([OH:5])=[O:4].[CH2:40](OC(=O)C(CC1C=CC(O)=CC=1)(OC1C=CC=CC=1)CC)C>>[O:33]([C:2]([CH2:6][C:7]1[CH:8]=[CH:9][C:10]([O:13][CH2:14][C:15](=[O:32])[NH:16][CH2:17][CH2:18][C:19]2[CH:24]=[CH:23][C:22]([O:25][C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=3)=[CH:21][CH:20]=2)=[CH:11][CH:12]=1)([CH2:1][CH3:40])[C:3]([OH:5])=[O:4])[C:34]1[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=1

Participants

3

Reactant 2

HCID 231327522-Methyl-2-phenoxy-3-(4-{[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-methoxy}-phenyl)-propionic acidHCID 69320315HCID 69320315, compound

Product 1

HCID 231327322-Phenoxy-2-(4-{[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-methoxy}-benzyl)-butyric acid

Procedure

The title compound was prepared using same method for 2-Methyl-2-phenoxy-3-(4-{[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-methoxy}-phenyl)-propionic acid from 2-(4-Hydroxy-benzyl)-2-phenoxy-butyric acid ethyl ester

Sources & evidence

ORD record
ord-5adeef95c0be4ecca95a9d218419d011
Source dataset
uspto-grants-2007_05
Patent number
US07220880B2

Reaction notes

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