HRID1353268

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(Cc1ccc(OCC(=O)NCCc2ccc(Oc3ccccc3)cc2)cc1)(Oc1ccccc1)C(=O)O

HCID23132752

未命名化合物

结构：CCOC(=O)C(C)(Cc1ccc(O)cc1)Oc1ccc(F)cc1

HCID69316070

未命名化合物

PRODUCTS

生成物

结构：CC(Cc1ccc(OCC(=O)NCCc2ccc(Oc3ccccc3)cc2)cc1)(Oc1ccc(F)cc1)C(=O)O

HCID23132709

未命名化合物

PROCEDURE

实验过程

The title compound was prepared using same method for 2-Methyl-2-phenoxy-3-(4-{[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-methoxy}-phenyl)-propionic acid from 2-(4-Fluoro-phenoxy)-3-(4-hydroxy-phenyl)-2-methyl-propionic acid ethyl ester.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a795c501dd7e4950a20fb974e23e75d4
来源数据集: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07220880B2
来源说明: uspto-grants-2007_05

反应 SMILES

[CH3:1][C:2]([O:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][C:15](=[O:32])[NH:16][CH2:17][CH2:18][C:19]2[CH:24]=[CH:23][C:22]([O:25][C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)=[CH:21][CH:20]=2)=[CH:9][CH:8]=1)[C:3]([OH:5])=[O:4].C(OC(=O)C(OC1C=CC([F:61])=CC=1)(C)CC1C=CC(O)=CC=1)C>>[F:61][C:37]1[CH:36]=[CH:35][C:34]([O:33][C:2]([CH3:1])([CH2:6][C:7]2[CH:8]=[CH:9][C:10]([O:13][CH2:14][C:15](=[O:32])[NH:16][CH2:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]([O:25][C:26]4[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=4)=[CH:21][CH:20]=3)=[CH:11][CH:12]=2)[C:3]([OH:5])=[O:4])=[CH:39][CH:38]=1