HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Fluorophenyl)piperazine → HCID 58646613, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Fluorophenyl)piperazine | HCID 70529 | — |
| Reactant | (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acid | HCID 9847886 | — |
| Reactant | (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester | HCID 58864673 | — |
| Product | HCID 58646613 | HCID 58646613 | — |
Reaction Steps
The title compound was prepared from (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester (PREPARATION 3, step 2) and 1-(2-fluoro-phenyl)-piperazine via the same procedure used for the preparation of (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a yellow oil. MS (ES) for C22H25FN2O5 [M+H]+: 417.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220880B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-16878c25baa142d5aa89ace7f5c9471d |
| Source note | uspto-grants-2007_05 |