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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353281Generated: October 31, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 58646619, compound

https://huagongshe.com/reaction/1353281

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant(2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acidHCID 9847886—
Reactant(2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl esterHCID 58864673—
ProductHCID 58646619HCID 58646619—

Reaction Steps

The title compound was prepared from (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester (PREPARATION 3, step 2) and C-benzo[1,3]dioxol-5-yl-methylamine via the same procedure used for the preparation of (2S,1R)-2-Ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a colorless oil. MS (ES) for C20H21NO7 [M+H]+: 388.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220880B2
Source datasetuspto-grants-2007_05
ORD IDord-01113bc8ff6940e9866039834f02eec5
Source noteuspto-grants-2007_05