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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353290Generated: October 31, 2026

2-Amino-6-fluorobenzothiazole → HCID 58646597, compound

https://huagongshe.com/reaction/1353290

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-6-fluorobenzothiazoleHCID 319954—
Reactant(2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acidHCID 9847886—
Reactant(2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl esterHCID 58864673—
ProductHCID 58646597HCID 58646597—

Reaction Steps

The title compound was prepared from (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester (PREPARATION 3, step 2) and 6-fluoro-benzothiazol-2-ylamine via the same procedure used for the preparation of (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a colorless oil. MS (ES) for C19H17FN2O5S [M+H]+: 405.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220880B2
Source datasetuspto-grants-2007_05
ORD IDord-452bcd3730994bad934b07ae1ae67a03
Source noteuspto-grants-2007_05