HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Cyclopropyl-1,3,4-thiadiazol-2-amine → HCID 21102603, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Cyclopropyl-1,3,4-thiadiazol-2-amine | HCID 717021 | — |
| Reactant | (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acid | HCID 9847886 | — |
| Reactant | (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester | HCID 58864673 | — |
| Product | HCID 21102603 | HCID 21102603 | — |
Reaction Steps
The title compound was prepared from (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester (PREPARATION 3, step 2) and 5-cyclopropyl-[1,3,4]thiadiazol-2-ylamine via the same procedure used for the preparation of (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a colorless oil. MS (ES) for C17H19N3O5S [M−H]−: 376.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220880B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-7a8760e9c953478187bc2d8d81959733 |
| Source note | uspto-grants-2007_05 |