(2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acid → HCID 23132714, compound

HRID 1353307Notes

Reaction equation

HRID 1353307 reaction equation
[CH2:1]([NH2:8])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].C[O:10][C:11](=[O:28])[C:12]([O:26][CH3:27])([CH3:25])[CH2:13][C:14]1[CH:19]=[CH:18][C:17]([O:20][CH2:21][C:22](O)=[O:23])=[CH:16][CH:15]=1.C(O[C@@H](CC1C=CC(O[C@@H](C(=O)NCCC2C=CC(OC3C=CC=CC=3)=CC=2)C)=CC=1)C(O)=O)C>>[CH2:1]([NH:8][C:22]([CH2:21][O:20][C:17]1[CH:16]=[CH:15][C:14]([CH2:13][C:12]([O:26][CH3:27])([CH3:25])[C:11]([OH:28])=[O:10])=[CH:19][CH:18]=1)=[O:23])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

Participants

3

Reactant 2

HCID 9847886(2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acidHCID 69416591HCID 69416591, compound

Product 1

HCID 23132714HCID 23132714, compound

Procedure

The title compound was prepared from 3-(4-carboxymethoxy-phenyl)-2-methoxy-2-methyl-propionic acid methyl ester heptyl amine via the same procedure used for the preparation of (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a colorless oil.

Workup

  1. customto produce a colorless oil

Sources & evidence

ORD record
ord-e6d877546f134238872641b615512890
Source dataset
uspto-grants-2007_05
Patent number
US07220880B2

Reaction notes

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