HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenyl isocyanate → HCID 21101734, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenyl isocyanate | HCID 70955 | — |
| Reactant | HCID 21101955 | HCID 21101955 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21101734 | HCID 21101734 | — |
Reaction Steps
5-Chloro-2-methyl-4-(piperazin-1-yl)quinoline (0.18 g, 0.7 mmol), 4-fluorophenyl isocyanate (91 μL, 0.8 mmol), and DMAP (5 mg) in CH2Cl2 (10 mL) are reacted according to method C yielding the product as a colorless solid after column chromatography with hexane-EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-49b5cec3cf3949b086395a5bd02ba716 |
| Source note | uspto-grants-2007_05 |