HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenyl isocyanate → HCID 21101787, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenyl isocyanate | HCID 70955 | — |
| Reactant | HCID 21101967 | HCID 21101967 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21101787 | HCID 21101787 | — |
Reaction Steps
7-Chloro-8-methyl-4-(piperazin-1-yl)quinoline (80 mg, 0.31 mmol), 4-fluorophenyl isocyanate (57 μL, 0.5 mmol), and DMAP (2 mg) in THF (10 mL) are reacted according to method C yielding the product as a yellow solid after column chromatography with hexane-EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-ac47a97fc41e42a38c1b5d9680f79728 |
| Source note | uspto-grants-2007_05 |