HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenyl isocyanate → HCID 21101811, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenyl isocyanate | HCID 70955 | — |
| Reactant | HCID 21101966 | HCID 21101966 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21101811 | HCID 21101811 | — |
Reaction Steps
7-Chloro-6-fluoro-4-(piperazin-1-yl)quinoline (0.36 g, 1.35 mmol) and 4-fluorophenyl isocyanate (171 μL, 1.5 mmol) in THF (10 mL) are reacted according to method C yielding the product as a colorless solid after column chromatography with hexane-EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-8a77006744624aff88cfc19e2e1190e8 |
| Source note | uspto-grants-2007_05 |