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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 135333Generated: October 30, 2026

N-methyl-2-pyrrolidone → 4-[(2-Hydroxy-ethyl)-thiophen-2-ylmethyl-amino]-6-methyl-2-(2,4,6-trimethyl-phenoxy)-nicotinic acid methyl ester

https://huagongshe.com/reaction/135333

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-pyrrolidoneHCID 13387—
Reactant2-[(Thiophen-2-ylmethyl)-amino]-ethanolHCID 3154448—
Reactant4-Chloro-2-(2,4,6-trimethyl-phenoxy)-6-methyl-nicotinic acid methyl esterHCID 24805651—
Product4-[(2-Hydroxy-ethyl)-thiophen-2-ylmethyl-amino]-6-methyl-2-(2,4,6-trimethyl-phenoxy)-nicotinic acid methyl esterHCID 69587833—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-5dd14ce263d24e489f9df11ed9c3647a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)